Cedars-Sinai receives $1.2M grant from California Initiative to Advance Precision Medicine
By a
In this study, the research team will look for the earliest signs of cardiovascular disease by monitoring patients remotely with a specialized watch that measures activity, sleep, heart rate and stress levels. Participants also will report their levels of anxiety, depression and quality of life using a smartphone or computer. Additionally, patients will send researchers finger prick blood samples by mail, allowing doctors to assess a variety of biomarkers and measure more than 500 blood proteins.
By combining these different types of data and integrating them into patients' medical records, the researchers will seek a "signal in the noise" that can predict who may be about to have a heart attack or stroke, empowering patients to better manage their conditions. The team also will measure the cost-effectiveness of this approach and whether it could be covered by insurance companies and other payers.
The Cedars-Sinai study aims to address a major national health issue: Cardiovascular disease is the leading cause of death for both men and women in
"The Governor's precision medicine initiative creates an amazing opportunity to confront this leading health threat by leveraging team science and advanced data analytics in ways never before possible," said
Funding for the study comes from the California
The research reflects a broad national push to combine emerging technology and medicine for the benefit of patients. Precision medicine aims to use data driven tools and analysis to develop new diagnostics, therapies and insights into disease. The teams in the
"Despite effective medical therapies and lifestyle interventions, many heart disease patients still progress due to under-treatment, poor adherence to treatment or failure to recognize clinical or biochemical clues that warn of heart attacks, strokes and heart failure," said
The key is identifying new predictive blood biomarkers earlier, said another co-principal investigator
The Cedars-Sinai team also includes researchers
The study also has received funding from
"This study, across medical disciplines and in partnership with industry, addressing a critical clinical question, is an example of the outstanding projects that
Keywords for this news article include: Genetics, Cardiology, Heart Attack, Diagnostics and Screening,
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